The fundamental difference between Vendor Central and Seller Central is who will be selling your products. When you use Vendor Central, Amazon’s retail team buys and resells your products to their customers, with Seller Central, you are selling directly to customers on Amazon. There are pros and cons to both, but often, eliminating the middleman benefits both the buyer and the seller. The bottom line profit is more when it is divided less and you can directly control the customer service experience with seller central. But having the "sold by Amazon" stamp of approval often boosts customer confidence and there is less work on the inventory management side.